In modern analytical chemistry, life sciences, and laboratory applications, the reliability of experimental results depends heavily on the purity of water used. As analytical methods become increasingly sophisticated, even trace amounts of water impurities can significantly impact experimental accuracy, potentially leading to costly repeat analyses. Therefore, a consistent supply of high-quality water is essential for ensuring experimental reproducibility and reliable results.

Consider this scenario: A researcher spends weeks conducting cell culture experiments, only to discover that the results cannot be replicated—with the root cause traced to substandard water quality used in preparing the culture medium. Such cases of major consequences from minor oversights are not uncommon in laboratories, highlighting the vital importance of ultra-pure water systems in maintaining research quality.

Sartorius Arium® ultra-pure water systems represent a series of modular, customizable solutions designed to produce ASTM Type I standard ultra-pure water. These systems can be configured according to a laboratory's daily water consumption, feedwater quality, and application types, with optional UV lamps and ultrafilters to meet various needs—from general laboratory use to sensitive analytical techniques and life science research.

Sartorius offers multiple Arium® ultra-pure water systems to accommodate different laboratory requirements:

• Arium® Mini: A compact Type 1 laboratory ultra-pure water system suitable for low to medium daily water consumption.
• Arium® Mini Extend: A reliable Type 1 ultra-pure water system offering greater flexibility.
• Arium® Pro: Designed for medium to high daily water consumption, producing ASTM Type 1 ultra-pure water.
• Arium® Comfort: An all-in-one laboratory water system capable of producing ASTM Type 1 ultra-pure water along with Type 2 or Type 3 purified water from tap water.
• Arium® Smart Station: A flexible distribution solution that can be paired with Arium® Pro and Arium® Comfort systems for purified and ultra-pure water distribution.
• Arium® Bagtanks: An innovative closed-system solution for storing purified water, preventing secondary contamination while maintaining water quality.

Ultra-pure water (Type 1) refers to water completely free from organic and inorganic contaminants, particulates, bacteria, and pyrogens. It is crucial for high-sensitivity applications such as HPLC, PCR, cell culture, and ICP-MS, where even minute impurities can compromise results. In these applications, ultra-pure water plays a pivotal role:

• HPLC (High-Performance Liquid Chromatography): As a component of the mobile phase, ultra-pure water ensures clear, accurate chromatographic peaks by eliminating interference from impurities.
• PCR (Polymerase Chain Reaction): Used in preparing PCR reaction systems, ultra-pure water prevents contamination from exogenous DNA or RNA, ensuring reliable amplification results.
• Cell Culture: When used in preparing cell culture media, ultra-pure water prevents harmful substances from affecting cell growth and viability, ensuring successful cell experiments.
• ICP-MS (Inductively Coupled Plasma Mass Spectrometry): Ultra-pure water used for sample dilution reduces background noise, enhances detection sensitivity, and guarantees accurate elemental analysis.

Sartorius Arium® ultra-pure water systems offer several key advantages:

• Exceptional Water Quality: Consistently produces ASTM Type 1 standard ultra-pure water with resistivity up to 18.2 MΩ·cm and TOC levels as low as ≤ 2 ppb.
• Modular Design: Customizable to specific laboratory needs with flexible component and function selection.
• User-Friendly Operation: Features plug-and-play installation, intuitive touchscreen interfaces, and tool-free consumable replacement for simplified operation and maintenance.
• Real-Time Monitoring: Continuously tracks critical parameters including resistivity, TOC, and flow rate to ensure stable, reliable water quality.
• Regulatory Compliance: Meets or exceeds ASTM Type 1, ISO 3696, and CLSI guidelines, making them suitable for regulated laboratories in pharmaceuticals, biotechnology, and academic research.

When choosing a Sartorius ultra-pure water system, consider these factors:

1. Daily Water Consumption: Select a system model based on your laboratory's daily water needs. The Arium® Mini suits low to medium consumption, while the Arium® Pro accommodates medium to high volumes.
2. Feedwater Quality: Assess your laboratory's feedwater quality to determine necessary pretreatment modules. Poor feedwater may require additional pretreatment steps like reverse osmosis or deionization.
3. Application Type: Choose system configurations based on intended applications. For life sciences, systems with ultrafilters are recommended to remove endotoxins, RNases, DNases, and proteases. For analytical chemistry, systems with low TOC levels are preferable.
4. Special Requirements: Consider specific needs such as remote distribution, data logging, and alarm functions. The Arium® Smart Station provides flexible distribution solutions for various laboratory layouts.

Selecting an appropriate ultra-pure water system is fundamental to ensuring reliable laboratory results. Sartorius Arium® ultra-pure water systems offer a range of modular, customizable solutions tailored to diverse laboratory requirements. By carefully evaluating daily water consumption, feedwater quality, application types, and special needs, laboratories can identify the optimal system to guarantee accurate, reproducible experimental outcomes—ultimately enhancing research efficiency and quality.